Piperidine

CAS RN:110-89-4

Environmental Fate

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 68(SRC), determined from a log Kow of 0.84(2) and a regression-derived equation(3), indicates that piperidine is expected to have high mobility in soil(SRC). However, the pKa of piperidine is 11.28(4), indicating that this compound will primarily exist in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Cations do not volatilize from moist soil surfaces. Piperidine is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 32.1 mm Hg(6). A 66.9 % theoretical BOD in 2 weeks using an activated sludge inoculum and the Japanese MITI test(7) indicates that biodegradation may be an important environmental fate process in soil(SRC).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 68(SRC), determined from a log Kow of 0.84(2) and a regression-derived equation(3), indicates that piperidine is not expected to adsorb to suspended solids and sediment(SRC). A pKa of 11.28(4) indicates piperidine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Piperidine was found to degrade anaerobically via denitrification in 12-15 days in microbial consortia from freshwater sediments, estuarine sediments and activated sludge(8).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), piperidine, which has a vapor pressure of 32.1 mm Hg at 25 deg C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase piperidine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 hours(SRC), calculated from its rate constant of 8.9X10-11 cu cm/molecule-sec at 25 deg C(SRC) that was derived using a structure estimation method(3).
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