Triethylamine

/Triethylamine/ is strongly alkaline, and when drop is applied to rabbit's eye, causes severe injury, graded 9 on scale of 1 to 10 after 24 hr /most severe injuries have been rated 10/. Tests of aqueaous solution on rabbit eyes at pH 10 and pH 11 indicate injuriousness /of triethylamine/ is related principally to degree of alkalinity.

A 70% solution applied on the skin of guinea pigs caused prompt skin burns leading to necrosis; when held in contact with guinea pig skin for 2 hr, there was severe skin irritation with extensive necrosis and deep scarring.