2,4-Toluene Diisocyanate

CAS RN:584-84-9

GHS Classification

Signal: Danger
GHS Hazard Statements
Aggregated GHS information provided by 930 companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 1 of 930 companies. For more detailed information, please visit ECHA C&L website

Of the 27 notification(s) provided by 929 of 930 companies with hazard statement code(s):

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H318 (38.21%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H319 (61.79%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]
H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
H335 (99.78%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]
H412 (94.73%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P201, P202, P260, P261, P264, P271, P272, P273, P280, P281, P284, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P308+P313, P310, P312, P320, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]

Precautionary Statement Codes
P261, P264, P272, P280, P285, P302+P352, P304+P341, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
Aggregated GHS information provided by 171 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 2 of 171 companies. For more detailed information, please visit ECHA C&L website

Of the 3 notification(s) provided by 169 of 171 companies with hazard statement code(s):

H317 (86.39%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H318 (13.61%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H319 (86.39%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P261, P264, P272, P280, P302+P352, P305+P351+P338, P310, P321, P333+P313, P337+P313, P363, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
H315: Causes skin irritation [Warning Skin corrosion/irritation]
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H330: Fatal if inhaled [Danger Acute toxicity, inhalation]
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H351: Suspected of causing cancer [Warning Carcinogenicity]
H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statement Codes
P201, P202, P260, P261, P264, P271, P272, P273, P280, P281, P284, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P308+P313, P310, P312, P320, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
H315: Causes skin irritation [Warning Skin corrosion/irritation]
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H330: Fatal if inhaled [Danger Acute toxicity, inhalation]
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
H351: Suspected of causing cancer [Warning Carcinogenicity]
H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]
H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statement Codes
P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P284, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P308+P313, P310, P314, P320, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found here.)
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed