2,4-Toluene Diisocyanate

CAS RN:584-84-9

DOT Emergency Guidelines

GUIDE 156
SUBSTANCES - TOXIC and/or CORROSIVE (Combustible / Water-Sensitive)
POTENTIAL HAZARDS
FIRE OR EXPLOSION
· Combustible material: may burn but does not ignite readily.
· Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
· When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards.
· Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks).
· Vapors may travel to source of ignition and flash back.
· Contact with metals may evolve flammable hydrogen gas.
· Containers may explode when heated or if contaminated with water.
HEALTH
· TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death.
· Contact with molten substance may cause severe burns to skin and eyes.
· Reaction with water or moist air will release toxic, corrosive or flammable gases.
· Reaction with water may generate much heat that will increase the concentration of fumes in the air.
· Fire will produce irritating, corrosive and/or toxic gases.
· Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
PUBLIC SAFETY
· CALL EMERGENCY RESPONSE Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
· Keep unauthorized personnel away.
· Stay upwind, uphill and/or upstream.
· Ventilate enclosed areas.
PROTECTIVE CLOTHING
· Wear positive pressure self-contained breathing apparatus (SCBA).
· Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
· Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
EVACUATION
Spill
· See the Initial Isolation and Protective Action Distances for highlighted materials. For non-highlighted materials, increase, in the downwind direction, as necessary, the isolation distance shown under "PUBLIC SAFETY".
Fire
· If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping document and/or the Canada and United States National Response Centers reference document.
EMERGENCY RESPONSE
FIRE
· Note: Most foams will react with the material and release corrosive/toxic gases.
Small Fire
· CO2, dry chemical, dry sand, alcohol-resistant foam.
Large Fire
· Water spray, fog or alcohol-resistant foam.
· FOR CHLOROSILANES, DO NOT USE WATER; use AFFF alcohol-resistant medium-expansion foam.
· Move containers from fire area if you can do it without risk.
· Use water spray or fog; do not use straight streams.
Fire involving Tanks or Car/Trailer Loads
· Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
· Do not get water inside containers.
· Cool containers with flooding quantities of water until well after fire is out.
· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
· ALWAYS stay away from tanks engulfed in fire.
SPILL OR LEAK
· ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
· All equipment used when handling the product must be grounded.
· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
· Stop leak if you can do it without risk.
· A vapor-suppressing foam may be used to reduce vapors.
· FOR CHLOROSILANES, use AFFF alcohol-resistant medium-expansion foam to reduce vapors.
· DO NOT GET WATER on spilled substance or inside containers.
· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.
· Prevent entry into waterways, sewers, basements or confined areas.
Small Spill
· Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.
· Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.
FIRST AID
· Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.
· Move victim to fresh air.
· Call 911 or emergency medical service.
· Give artificial respiration if victim is not breathing.
· Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
· Administer oxygen if breathing is difficult.
· Remove and isolate contaminated clothing and shoes.
· In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
· For minor skin contact, avoid spreading material on unaffected skin.
· Keep victim calm and warm.
· Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
ERG 2016

Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed