2,4-Toluene Diisocyanate

CAS RN:584-84-9

Other Preventive Measures

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.
SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants. Ensure that the local ventilation moves the contaminant away from the worker.
The worker should immediately wash the skin when it becomes contaminated.
The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.
Work clothing that becomes wet or significantly contaminated should be removed and replaced.
Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. /Toluene diisocyanate/
Personnel protection: Avoid breathing vapors. Keep upwind. ... Avoid bodily contact with the material. Do not handle broken packages unless wearing appropriate personnel protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. /Toluene diisocyanate/
Because pulmonary effects can be produced in man at very low levels in air, toluene diisocyanate should be used only in areas with adequate general and local ventilation ... . /Toluene diisocyanate/
The open points at the interface between different forms of protective clothing, e.g., the opening that forms between the sleeve of a protective suit and a glove, should be sealed to prevent exposure through the interface. A common and effective method for sealing these interfaces is to use duct tape to join the two different forms of protective clothing. /Isocyanate-containing substances/
NIOSH recommends that employers provide workers with appropriate training on the inhalation and dermal exposure hazards associated with isocyanate-containing materials and on the proper use of personal protective equipment (PPE) associated with protection from these exposures. /Isocyanate-containing substances/
NIOSH recommends that empoloyers conduct industrial hygiene (IH) surveys on all workers potentially exposed to isocyanates. /Isocyanates/
NIOSH recommends both preplacement and periodic medical surveillance programs for all workers potentially exposed to diisocyanates. /Diisocyanates/
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed