Boron Trifluoride

CAS RN:7637-07-2

Health Effects

0.2.1 SUMMARY OF EXPOSURE
  • 0.2.1.1 ACUTE EXPOSURE
    • A) Boron trifluoride is a severe ocular and pulmonary system irritant. Dermal irritation and/or burns may occur.
    • B) It reacts in moist air to form boric acid, hydrogen fluoride, fluoroboric acid, and other products. Thus the respiratory passage (which contains moist air) may produce these products which would be free to react with tissue.
    • C) SYSTEMIC EFFECTS - BORON affects the central nervous system, leading to depressed blood pressure, persistent vomiting, and diarrhea.
    • D) INHALATION EXPOSURE - Acute exposure to boron trifluoride gas has resulted in loss of consciousness and hypoxemia.
    • E) DERMAL EXPOSURE - Boron trifluoride can burn the skin, and contact with the liquid may cause frostbite. It is absorbed through the skin.
  • 0.2.1.2 CHRONIC EXPOSURE
    • A) Lowered pulmonary function, dried mucous membranes and nosebleeds, severe irritation of the eyes and eyelids, as well as inflammation and congestion of the lungs may occur with chronic exposure to this compound .
0.2.4 HEENT
  • 0.2.4.1 ACUTE EXPOSURE
    • A) Teeth: Rats exposed to 15 to 100 ppm developed hypoplasia of the teeth and excessive fluoride deposition.
    • B) Eye irritation may occur from exposure to this gas.
    • C) Nose bleed and nasal dryness has been reported in humans.
0.2.6 RESPIRATORY
  • 0.2.6.1 ACUTE EXPOSURE
    • A) Acute inhalations have resulted in hypoxemia.
    • B) Pulmonary irritation is expected with inhalation. Pneumonitis has been reported in animals. Long term effects in humans are unclear. Physical examination of exposed workers appear to show some decrease in pulmonary function without positive x-ray findings.
  • 0.2.6.2 CHRONIC EXPOSURE
    • A) Physical examination of exposed workers appear to show some decrease in pulmonary function without positive x-ray findings.
0.2.7 NEUROLOGIC
  • 0.2.7.1 ACUTE EXPOSURE
    • A) Acute exposure to boron trifluoride gas has resulted in rapid loss of consciousness.
0.2.10 GENITOURINARY
  • 0.2.10.1 ACUTE EXPOSURE
    • A) Renal tubular degeneration has been reported in fatally poisoned animals.
0.2.12 FLUID-ELECTROLYTE
  • 0.2.12.1 ACUTE EXPOSURE
    • A) Hypophosphatemia, hypocalcemic and elevated fluoride levels have developed in animal studies.
  • 0.2.12.2 CHRONIC EXPOSURE
    • A) Phosphorous: Dogs exposed to 100 ppm for 30 days developed decreased blood phosphorous levels.
0.2.14 DERMATOLOGIC
  • 0.2.14.1 ACUTE EXPOSURE
    • A) Skin irritation is expected on contact. When soaked into a cotton ball and placed on the skin for 1 to 2 days, boron trifluoride left a HF type burn.
0.2.21 CARCINOGENICITY
  • 0.2.21.1 IARC CATEGORY
    • A) IARC Carcinogenicity Ratings for CAS7637-07-2 (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004):
      • 1) Not Listed
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