Boron Trifluoride

CAS RN:7637-07-2

Treatment Overview

  • A) INHALATION: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with an inhaled beta2-adrenergic agonist. Consider systemic corticosteroids in patients with significant bronchospasm.
  • B) ACUTE LUNG INJURY: Maintain ventilation and oxygenation and evaluate with frequent arterial blood gases and/or pulse oximetry monitoring. Early use of PEEP and mechanical ventilation may be needed.
  • C) OBSERVATION - Carefully observe patients with inhalation exposure for the development of abnormal systemic signs or symptoms and administer symptomatic treatment as necessary. Signs and symptoms of pulmonary edema may be delayed for 24 to 72 hours in some cases.
  • D) INITIAL TREATMENT - Mild inhalational symptoms may be treated with 2.5% calcium gluconate nebulization.
  • A) Irrigate promptly with crystalloid solution. Carefully evaluate for eye damage; exposure to dilute solutions may result in delayed signs and symptoms of ocular damage. The patient should be evaluated by an ophthalmologist following appropriate decontamination.
    • 1) There is no specific antidote. Treatment is directed at supporting respirations and limiting potential caustic damage.
    • 2) DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999).
    • 3) Dermal absorption is unlikely; however, in the event dermal absorption is suspected, refer to the management on HYDROFLUORIC ACID for additional information.
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