Hydrogen Bromide

CAS RN:10035-10-6

Range of Toxicity

A) TOXICITY: There is great interpatient variability in symptoms at a given serum bromide concentration. Most toxicity develops after chronic ingestion. Serum bromide concentrations of 50 to 100 mg/dL may be associated with symptoms; 200 mg/dL will produce toxic symptoms; 300 mg/dL may be fatal. Acute ingestion of 4500 mg bromovalerylurea caused lethargy and myoclonus in an adult. Chronic consumption of 0.5 to 1 g bromides/day may cause bromism.
B) THERAPEUTIC DOSE: Adults: Acceptable daily intake: 1 mg/kg.
A) TOXICITY: Serious burns are less likely if the pH >3. Injury is usually greater with either a large ingestion (usually deliberate), or a high concentration acid (usually not a household product). With highly concentrated liquids (eg, 20N), severe burns may occur in up to 100% of all patients.
B) In a case series of unintentional caustic ingestions (mixed liquid and solid, acids and bases) among children, the incidence of significant esophageal or gastric burns was 5% to 35%. However, adults with deliberate acid ingestions are more likely to develop significant esophageal and/or gastric burns (40% to 95%).
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