Calcium Nitrate

CAS RN:10124-37-5

Range of Toxicity

A) TOXIC DOSE: Persons who consume more than 10 g of CaCO3 (= 4 g Ca) are at risk of developing milk-alkali syndrome, but the condition has been reported in at least one person consuming only 2.5 g/day of CaCO3 ( =1 g Ca), an amount usually considered moderate and safe. Patients with predisposing conditions such as renal insufficiency may develop the syndrome after chronic ingestion of 5 to 10 g/day CaCO3, and those with dialysis dependent renal failure can develop hypercalcemia after 3.2 to 6.4 g/day. Normal total serum calcium concentrations are 9 to 10.4 mg/dL (4.5 to 5.2 mEq/L). Symptoms may appear when plasma calcium concentrations reach 6.6 mEq/L.
B) THERAPEUTIC DOSE: In cases of hyperkalemia, hypermagnesemia, or calcium channel blocker overdose, administer calcium gluconate or chloride: 1 to 2 g IV titrated to clinical response. In patents with severe calcium channel blocker overdose, higher doses of calcium may be needed. Calcium repletion: 1 to 2 g/day of elemental calcium.
A) TOXICITY: The minimum toxic dose of nitrite is extremely variable; the assessment of the severity of toxicity should be based on clinical findings in the majority of cases. The lowest reported lethal dose of oral sodium nitrite was a 1 g ingestion prior to death in a 17-year-old girl. THERAPEUTIC AND NORMAL DOSE RANGE: The acceptable daily intake of dietary nitrites (excluding infants under 6 months of age) is 0.4 mg/kg. Please refer to "SODIUM NITRITE" management for dosing information.
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed