Acrylamide

CAS RN:79-06-1

Protective Equipment / Clothing

Eye/face protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection: Handle with gloves.
Body Protection: Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Emergency response personal protective equipment: Wear full protective clothing and positive pressure self-contained breathing apparatus.
Prevent skin contact. 8 hr (More than 8 hr of resistance to breakthrough >0.1 micron>g/sq cm/min): butyl rubber gloves, suits, boots; Tychem 1000 suits; 4 hr (At least 4 but <8 hr of resistance to breakthrough >0.1 micron>g/sq cm/min): nitrile rubber gloves, suits, boots; polyvinyl chloride gloves, suits, boots; Viton gloves, suits; 4H and Silver Shield gloves. Engineering controls should be used wherever feasible to maintain airborne concentrations of this chemical below the prescribed exposure limit. Respirators and protective equipment are less effective than engineering controls and should be used only in nonroutine or emergency situations which may result in exposure concentrations in excess of the TWA environmental limit. Wear protective gloves and clothing to prevent repeated or prolonged skin contact. Wear dust-proof eye protection to prevent any reasonable probability of eye contact. ... Work clothing should be changed daily if clothing is contaminated. Remove nonimpervious clothing immediately if wet or contaminated.
Personnel protection: Wear appropriate chemical protective gloves, boots and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this chemical. /Acrylamide, solid or Acrylamide/
Respirator Recommendations: At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
Assigned Protection Factor (APF) Respirator Recommendations
APF = 10,000 Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode.
APF = 10,000 Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxillary self-contained positive-pressure breathing apparatus.
Respirator Recommendations: Escape Conditions:
Assigned Protection Factor (APF) Respirator Recommendations
APF = 50 Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus.
Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.]
Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection.
Wear appropriate eye protection to prevent eye contact.
Wear appropriate personal protective clothing to prevent skin contact.
Employees should be provided with and required to use impervious clothing, gloves, face-shields (eight-inch minimum), and other appropriate protective clothing necessary to prevent any possibility of skin contact with acrylamide. Employees should be provided with and required to use splash-proof goggles where there is any possibility of liquid acrylamide contacting the eyes.
PRECAUTIONS FOR "CARCINOGENS": ... Dispensers of liq detergent /should be available./ ... Safety pipettes should be used for all pipetting. ... In animal laboratory, personnel should ... wear protective suits (preferably disposable, one-piece & close-fitting at ankles & wrists), gloves, hair covering & overshoes. ... In chemical laboratory, gloves & gowns should always be worn ... however, gloves should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, & disposable plastic aprons might provide addnl protection. ... gowns ... /should be/ of distinctive color, this is a reminder that they are not to be worn outside the laboratory. /Chemical Carcinogens/
The unloading station /for dry acrylamide/ should be equipped with an exhaust hood.
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed