Ethylene Oxide

CAS RN:75-21-8

GHS Classification

Signal: Danger
GHS Hazard Statements
H220: Extremely flammable gas [Danger Flammable gases]
H315: Causes skin irritation [Warning Skin corrosion/irritation]
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H340: May cause genetic defects [Danger Germ cell mutagenicity]
H350: May cause cancer [Danger Carcinogenicity]

Precautionary Statement Codes
P201, P202, P210, P261, P264, P271, P280, P281, P302+P352, P304+P340, P305+P351+P338, P308+P313, P311, P312, P321, P332+P313, P337+P313, P362, P377, P381, P403, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
Aggregated GHS information provided by 2704 companies from 36 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 1 of 2704 companies. For more detailed information, please visit ECHA C&L website

Of the 35 notification(s) provided by 2703 of 2704 companies with hazard statement code(s):

H220 (100%): Extremely flammable gas [Danger Flammable gases]
H230 (33.52%): May react explosively even in the absence of air [Flammable gases]
H280 (84.76%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]
H302 (78.73%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H331 (99.3%): Toxic if inhaled [Danger Acute toxicity, inhalation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H340 (100%): May cause genetic defects [Danger Germ cell mutagenicity]
H350 (100%): May cause cancer [Danger Carcinogenicity]
H372 (75.14%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P201, P202, P210, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P311, P312, P314, P321, P330, P332+P313, P337+P313, P362, P377, P381, P403, P403+P233, P405, P410+P403, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Warning
GHS Hazard Statements
Aggregated GHS information provided by 159 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 5 of 159 companies. For more detailed information, please visit ECHA C&L website

Of the 3 notification(s) provided by 154 of 159 companies with hazard statement code(s):

H315 (85.06%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (85.06%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H412 (10.39%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P362, P363, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
Aggregated GHS information provided by 76 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 1 of 76 companies. For more detailed information, please visit ECHA C&L website

Of the 2 notification(s) provided by 75 of 76 companies with hazard statement code(s):

H315 (52%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (52%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H318 (52%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H411 (48%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
H412 (52%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P333+P313, P362, P363, P391, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
H220: Extremely flammable gas [Danger Flammable gases]
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
H340: May cause genetic defects [Danger Germ cell mutagenicity]
H350: May cause cancer [Danger Carcinogenicity]
H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

Precautionary Statement Codes
P201, P202, P210, P260, P261, P264, P270, P271, P272, P280, P281, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P314, P321, P330, P333+P313, P363, P377, P381, P403, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found here.)
Signal: Danger
GHS Hazard Statements
H220: Extremely flammable gas [Danger Flammable gases]
H280: Contains gas under pressure; may explode if heated [Warning Gases under pressure]
H301: Toxic if swallowed [Danger Acute toxicity, oral]
H315: Causes skin irritation [Warning Skin corrosion/irritation]
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H340: May cause genetic defects [Danger Germ cell mutagenicity]
H350: May cause cancer [Danger Carcinogenicity]
H360: May damage fertility or the unborn child [Danger Reproductive toxicity]
H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]

Precautionary Statement Codes
P201, P202, P210, P260, P261, P264, P270, P271, P272, P273, P280, P281, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P311, P312, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P377, P381, P403, P403+P233, P405, P410+P403, and P501
(The corresponding statement to each P-code can be found here.)
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed