Ethylene Oxide

CAS RN:75-21-8

Protective Equipment / Clothing

NIOSH: 5 ppm: GMFS+ (any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern); or SCBAF (any self-contained breathing apparatus with a full facepiece); or SAF (any supplied-air respirator with a full facepiece). Emergency or planned entry into unknown concentrations or IDLH conditions: SCBAF:PD,PP (any self-breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode); or SAF:PD, PP: ASCBA (any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in a pressure-demand or other positive pressure mode). Escape: GMFS+ {any air-purifying, full facepiece respirator (gas mask) with a chin-style, front- or back- mounted canister providing protection against the compound of concern); or SCBAE (any appropriate escape-type, self-contained breathing apparatus). (+ End of service life indicator (ESLI) required).
Air-supplied mask; goggles or face shield; rubber shoes & coveralls.
Wear neoprene gloves, safety glasses, plastic protective clothing and self-contained breathing apparatus.
PRECAUTIONS FOR "CARCINOGENS": ... Dispensers of liq detergent /should be available./ ... Safety pipettes should be used for all pipetting. ... In animal laboratory, personnel should ... wear protective suits (preferably disposable, one-piece & close-fitting at ankles & wrists), gloves, hair covering & overshoes. ... In chemical laboratory, gloves & gowns should always be worn ... however, gloves should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, & disposable plastic aprons might provide addnl protection. ... gowns ... /should be/ of distinctive color, this is a reminder that they are not to be worn outside the laboratory. /Chemical Carcinogens/
A study was conducted to evaluate protective clothing garment materials used by emergency response personnel and to determine their effectiveness when combating ammonia or ethylene oxide in gaseous form. Data were collected using an automated permeation test system for 13 garment materials representing 11 types of total encapsulating suit materials and two glove materials. For the study neat (100%) and 2000 ppm (0.2%) gas were chosen as challenge concentrations. A closed loop test system was chosen for the study using an infrared detector. Breakthrough times and steady state permeation rates were determined. The results indicated suitable garment materials were found to protect workers against 100% anhydrous ammonia for an extended time period and there was also a large selection of materials for 0.2% ammonia. Surgical latex was not recommened for protection against ammonia. While several materials offered resonable working time protection against 100% ethylene oxide, only two of the 17 materials were useful for extended time periods. The semiautomated test system expedited chemical permeation resistance testing and proved to be effective in securing the needed data.
Wear appropriate personal protective clothing to prevent skin contact. /Liquid/
Wear appropriate eye protection to prevent eye contact. /Liquid/
Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] /Liquid/
Respirator Recommendations: Up to 5 ppm
Assigned Protection Factor (APF) Respirator Recommendation
APF = 50 Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern. End of service life indicator (ESLI) required.
APF = 50 Any self-contained breathing apparatus with a full facepiece.
APF = 50 Any supplied-air respirator with a full facepiece.
Respirator Recommendations: Emergency or planned entry into unknown concentrations or IDLH conditions:
Assigned Protection Factor (APF) Respirator Recommendation
APF = 10,000 Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode.
APF = 10,000 Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus.
Respirator Recommendations: Escape conditions:
Assigned Protection Factor (APF) Respirator Recommendation
APF = 50 Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern. End of service life indicator (ESLI) required./Any appropriate escape-type, self-contained breathing apparatus.
Wear special protective clothing and positive pressure self-contained breathing apparatus.
Personnel protection: ... Wear positive pressure self-contained breathing apparatus. ... Wear appropriate chemical protective clothing. /Ethylene oxide or ethylene oxide with nitrogen/
Find more information on this substance at: Hazardous Substances Data Bank , TOXNET , PubMed