Acetamide

CAS RN: 60-35-5

Key Info

CLINICAL EFFECTS

0.2.1 SUMMARY OF EXPOSURE

0.2.1.1 ACUTE EXPOSURE
A) USES: Irritants are a broad category of substances that cause inflammation and swelling but not cellular death or tissue damage,
while corrosives cause cellular damage and death. Whether a substance is labeled a "corrosive" or "irritant" typically depends
on several factors including concentration, viscosity, pH, molarity, oxidation-reduction potential, complexing affinity toward
bivalent ions, etc. It can be difficult to determine whether a substance is a corrosive or irritant and the distinction may be
concentration-dependent.
B) TOXICOLOGY: Irritants cause inflammation and swelling with local tissue irritation; this can lead to rhinorrhea, cough, shortness
of breath, bronchospasm, irritation of oral mucous membranes and esophagus, and rarely upper airway swelling or acute lung injury.
C) WITH POISONING/EXPOSURE
1) MILD TO MODERATE TOXICITY: Irritants may cause swelling, redness, and pain at any site, especially at mucous membranes. The
mouth, nose, and eyes are commonly affected. After inhalation, cough, tachypnea, and wheezing are common. With ingestion, nausea,
vomiting, and diarrhea are common. With dermal exposure, redness, swelling, and pain may occur.

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