Sodium Thiosulfate

Key Info

0.2.1 SUMMARY OF EXPOSURE

0.2.1.1 ACUTE EXPOSURE
A) ANIMAL STUDIES
1) Rapid intravenous infusion of large amounts has caused transient hypotension and ECG changes in dogs.
2) Metabolic acidosis and hypernatremia occurred in dogs given large doses.
B) WITH POISONING/EXPOSURE
1) Sodium thiosulfate is an agent with a low order of toxicity. It may be a mild irritant in the solid form. Ingestion can cause gastrointestinal disturbances. It can cause allergic dermatitis.
2) Ingestion of a large quantity may cause diarrhea.