Ozone

CAS RN: 10028-15-6

Key Info

CLINICAL EFFECTS

0.2.1 SUMMARY OF EXPOSURE

0.2.1.1 ACUTE EXPOSURE
A) Ozone is a skin, eye, upper respiratory tract, and mucous membrane irritant. The primary symptoms after acute exposure are
irritation of the eyes, nose, throat, and chest, as well as fatigue. Exposure to less than 0.5 ppm may produce symptoms and alter
pulmonary function tests, but does not significantly decrease exercise potential.
B) The primary site of acute injury is the lung; injury is characterized by pulmonary congestion, edema, and hemorrhage.
C) Human systemic effects by inhalation: visual field changes, lacrimation, headache, decreased pulse rate, decreased blood pressure,
dermatitis, cough, dyspnea, respiratory stimulation, and other pulmonary changes.
D) Ozone increases bronchial allergen responses in subjects with allergic asthma or rhinitis.
E) The toxicity of ozone is increased by its interaction with other environmental oxidants.
F) OZONE THERAPY: Intraarticular ozone infiltrations in 2 patients resulted in cortical blindness and seizures.

REACTIVITIES & INCOMPATIBILITIES

All oxidizable materials (both organic and inorganic).
Explosive with alkenes, aromatic compounds, bromine, combustible gasses, diethyl ether, hydrogen bromide, isopropylidene compounds.

Dangerous /fire hazard/ by chemical reaction with aniline, benzene, bromide, (diallyl methyl carbinol + acetic acid), diethyl
ether, nitrogen pentoxide, ethylene, hydrogen bromide, hydrogen iodide, nitrogen dioxide, nitric oxide, nitrogen chloride, NI3,
nitroglycerin, organic liquids, organic matter, antimony.
/Other/ incompatabilities: Alkenes, aromatic compounds, rubber, dicyanogen, dinitrogen tetroxide, 4-hydroxy-4-methyl-1,6-heptadiene,
nitrogen trichloride, stibine, tetrafluorohydrazine.

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