Propionic Anhydride

CAS RN: 123-62-6

Exposure Summary

Propionic anhydride's production and use as an esterifying agent for perfume oils, fats, cellulose, alkylated resins, dyestuffs, drugs and as a dehydrating agent may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 1.36 mm Hg at 25 deg C indicates propionic anhydride will exist solely as a vapor in the ambient atmosphere. Vapor-phase propionic anhydride will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 17 days. Photolysis of propionic anhydride is not expected to be an important environmetnal fate process due to the rapid hydrolysis rate. Acid anhydrides react with water to form the corresponding acid. Propionic anhydride is expected to hydrolyze rapidly with estimated half-lives of 10 and 1.0 minutes, at pH 7 and 8, respectively. Biodegradation, adsorption, bioconcentration and volatilization from moist soil or water surfaces are not expected to be important fate processes due to the rapid hydrolysis of propionic anhydride. However, propionic anhydride may volatilize from dry soil surfaces based upon a vapor pressure of 1.36 mm Hg at 25 deg C. Occupational exposure to propionic anhydride may occur through inhalation and dermal contact with this compound at workplaces where propionic anhydride is produced or used. (SRC)
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