Acetone

CAS RN: 67-64-1

Range of Toxicity

A) Ingestion of 200 mL (2 to 3 mL/kg) produced coma, hyperglycemia, and acetonuria in an adult.
B) In a 30-month-old child, approximately 180 mL of nail polish remover (65% acetone, 10% isopropyl alcohol) caused severe toxicity (ie, seizures, CNS and respiratory depression, hypothermia, hyperglycemia, ketonemia, acidosis).
C) Ingestion of small amounts of acetone (volume and concentration) such as that found in fingernail preparations generally does not cause significant toxicity except in very young children.
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