Arsine

CAS RN: 7784-42-1

Laboratory

A) Monitor serial CBC, serum electrolytes, renal function, bilirubin, LDH, aminotransferases, CK, urinalysis, and urine output.
B) Monitor vital signs.
C) Obtain an ECG and initiate continuous cardiac monitoring. Monitor serial ECGs for evidence of acute hyperkalemia.
D) Monitor free plasma or serum hemoglobin. Coombs tests are negative and generally not helpful.
E) Blood and urine arsenic concentrations are generally elevated but are not useful to guide therapy. A 24-hour urinary arsenic may help evaluate chronic exposure.
F) Obtain a chest radiograph in patients with pulmonary symptoms.
G) Routine chronic monitoring for work exposure should include periodic blood counts with red cell indices, urinalysis and 24-hour quantitative urine for arsenic. This should be done every 6 months.
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