Phosphine

CAS RN: 7803-51-2
UN/NA: 2199

Range of Toxicity

A) TOXICITY: Occupational exposure limits established by various agencies include NIOSH REL of a 10-hour TWA of 0.3 parts per million (ppm) and 15 minute STEL of 1 ppm, OSHA PEL of an 8-hour TWA of 0.3 ppm, ACGIH TLV 8-hour TWA of 0.3 ppm and 15 minute STEL of 1 ppm, and NIOSH has designated 50 ppm as immediately dangerous to life and health. There have been case reports of a physician being symptomatic after exposure to phosphine released from the excised stomach of a patient who died from aluminum phosphide poisoning. A forensic specialist, investigating a methamphetamine lab, who was exposed to 2.7 ppm phosphine for 20 to 30 minutes without respiratory protection, and subsequently developed dizziness, cough, headache, and diarrhea, and had rhonchi on physical exam. Occupational exposure to phosphine at airborne concentrations of 0.17 to 2.11 ppm during aluminum phosphide grain fumigation resulted in the development of cough, dyspnea, chest tightness, headache, giddiness, numbness, lethargy, anorexia, and epigastric pain.
Find more information on this substance at: PubChem, PubMed