VX

A) TOXICITY: A very small drop on the skin may cause sweating and twitching at the site, while a small drop on skin may cause nausea, vomiting and diarrhea. A larger drop on the skin may cause loss of consciousness, seizures, apnea, and flaccid paralysis. VX is 100 times as toxic to humans as sarin (GB). VX is 300 times more lethal than tabun on skin. Sarin has an especially rapid onset of action. On a weight basis it is less potent than VX. A drop of the liquid on skin may be sufficient to cause death. Soman (GD) is an extremely potent nerve agent, with a human lethal dose as low as 0.01 mg/kg. On a weight basis, soman is less potent than VX, but more potent than sarin or tabun. It can be hazardous by any route of exposure. Tabun (GA) has an especially rapid onset of action, which on a weight basis is less potent than VX. The human fatal dose has been reported to be 0.01 mg/kg. On a weight basis, toxicity in descending order is: VX>soman=GF>sarin>tabun.