Acetonitrile

NIOSH: 200 ppm: CcrOV (APF = 10) [any air-purifying half-mask respirator equipped with an organic vapor cartridge(s)]; Sa APF = 10) (any supplied-air respirator); or SCBA (any self-contained breathing apparatus); 500 ppm: Sa:Cf (APF = 25) (any supplied-air respirator operated in a continous-flow mode); or PaprOv (APF = 25) [any powered, air-purifying respirator with organic vapor cartridge(s)]; or CcrFOv (APF = 50) [any powered, air- purifying respirator with organic vapor cartridge(s)]; or CcrFOv (APF = 50) [any chemical cartridge respirator with a full face-piece and organic vapor cartridge(s)]; or GmFOv (APF = 50) [any air-purifying, full-face-piece respirator (gas mask) with a chin-style, front- or back-mounted acid gas canister]; or ScbaF 9APF = 50) (any self-contained breathing apparatus with a full face-piece); or SaF (APF = 50) (any supplied-air respirator with a full face-piece). Emergency or planned entry into unknown concentrations or IDLH conditions: ScbaF:Pd,Pp (APF = 10,000) (any self-contained breathing apparatus that has a full face-piece and is operated in a pressure-demand or other positive-pressure mode); or SaF:Pd,Pp:AScba (APF = 10,000) (any supplied-air respirator that has a full face-piece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in a pressure-demand or other positive-pressure mode). Escape: GmFOv (APF = 50) [any air-purifying, full-face-piece respirator (gas mask) with a chin-style, front- or back-, mounted organiv vapor canister); or ScbaE (any escape-type, self-contained breathing apparatus).

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Wear appropriate personal protective clothing to prevent skin contact.

Wear appropriate eye protection to prevent eye contact.

Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.]

If the use of respirators is necessary, the only respirators permitted are those that have been approved by the Mine Safety and Health Administration ... or by the National Institute for Occupational Safety and Health. ... Employees should be provided with and required to use impervious clothing, gloves, face shields (eight-inch minimum), and other appropriate protective clothing necessary to prevent repeated or prolonged skin contact with liquid acetonitrile. ... Employees should be provided with and required to use splash-proof safety goggles where liquid acetonitrile may contact the eyes.

Complete suit protecting against chemicals, flame retardant antistatic protective clothing, the type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Personnel protection: ... Wear positive pressure self-contained breathing apparatus. ... Wear appropriate chemical protective gloves, boots and goggles.

Wear full protective clothing and positive pressure self-contained breathing apparatus. Butyl rubber barrier recommnded

Respirator Recommendations: Up to 200 ppm

Assigned Protection Factor (APF)	Respirator Recommendation
APF = 10	Any chemical cartridge respirator with organic vapor cartridge(s).
APF = 10	Any supplied-air respirator.

Respirator Recommendations: Up to 500 ppm

Assigned Protection Factor (APF)	Respirator Recommendation
APF = 25	Any supplied-air respirator operated in a continuous-flow mode.
APF = 25	Any powered, air-purifying respirator with organic vapor cartridge(s).
APF = 50	Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s).
APF = 50	Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister.
APF = 50	Any self-contained breathing apparatus with a full facepiece.
APF = 50	Any supplied-air respirator with a full facepiece.

Respirator Recommendations: Emergency or planned entry into unknown concentrations or IDLH conditions:

Assigned Protection Factor (APF)	Respirator Recommendation
APF = 10,000	Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode.
APF = 10,000	Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus.

Respirator Recommendations: Escape conditions:

Assigned Protection Factor (APF)	Respirator Recommendation
APF = 50	Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus.