Acetonitrile

CAS RN: 75-05-8

Carcinogenicity Evidence

Weight-of-Evidence Characterization Under the current Risk Assessment Guidelines (US EPA, 1987), ACN is assigned carcinogen class D, not classifiable as to human carcinogenicity. There is an absence of human evidence and the animal evidence is equivocal. Under the Proposed Guidelines for Carcinogen Risk Assessment (US EPA, 1996), the carcinogenic potential of ACN following inhalation, oral, or dermal exposure is best characterized as "cannot be determined because the existing evidence is composed of conflicting data (e.g., some evidence is suggestive of carcinogenic effects, but other equally pertinent evidence does not confirm any concern)." /Based on former classification guidelines/
A4: Not classifiable as a human carcinogen.
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