Glutaraldehyde

CAS RN: 111-30-8

Range of Toxicity

A) TOXICITY: A toxic dose has not been established in man. Ten percent solutions have caused dermatitis when applied therapeutically. Two percent solutions have caused ocular damage. One young adult intentionally ingested 75 mL of a glutaraldehyde 15% w/v and coco benzyl dimethyl ammonium chloride 10% w/v solution and developed metabolic acidosis and laryngeal edema. She required intubation and mechanical ventilation but recovered completely.
B) OCCUPATIONAL EXPOSURE: Glutaraldehyde has been used in the healthcare setting for high level disinfection and it is a known irritant of the skin, eyes, nose and lungs in some individuals. Healthcare personnel have developed allergic dermatitis, rhinitis and occupational asthma after chronic exposure.
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