1,2-Propanediol Dinitrate

A) Serum nitrite concentrations are not widely available or clinically useful.
B) Determine CBC and methemoglobin concentration in all cyanotic patients or patients with dyspnea or other signs of respiratory distress.
C) Arterial blood gases should be monitored in symptomatic or cyanotic patients. An arterial blood gas test will reveal a falsely normal calculated oxygen saturation despite low measured pulse oximetry. If oxygen saturation is measured, it will be low relative to the pO2. This saturation gap suggests methemoglobinemia.
D) Monitor vital signs.
E) Monitor renal function in symptomatic patients.
F) Monitor serum electrolyte status in patients with significant vomiting.
G) Monitor mental status and perform a neurologic exam in symptomatic patients.
H) Obtain an ECG and institute continuous cardiac monitoring in symptomatic patients.