Nerve Agents

ABC Reminders / Treatment


ABC Reminders

Quickly access airway patency. If trauma is suspected, maintain cervical immobilization manually and apply a cervical collar and a backboard when feasible. Ensure adequate respiration and pulse. Document oxygen saturation. Place on a cardiac monitor.

Link to Primary and Secondary Survey

If the patient is symptomatic, immediately institute emergency life support measures, including the use of nerve agent specific antidotes.

Advanced Treatment

In cases of respiratory compromise, secure airway and respiration via endotracheal intubation or laryngeal mask airway (LMA) (use Bag Valve Mask (BVM) if unable to secure airway). If clinically indicated, perform cricothyroidotomy or place 14 gauge intracath in the cricothryroid membrane (if equipped and trained to do so).

Link to 14 gauge intracath placement instructions.

Patients who are in cardiorespiratory failure or have seizures should be treated according to advanced life support (ALS) protocols.

Link to Basic and Advanced Life Support


If clinically indicated, initiate/repeat dosing of atropine and pralidoxime.

Link to Antidote Treatment in the Hot Zone

Find more information on this substance at: PubChem, PubMed