Lead Acetate

CAS RN: 301-04-2

Range of Toxicity

A) TOXICITY: Acute poisoning is rare, but death may occur in 1 to 2 days after the ingestion of 10 to 30 g of lead in an adult. Mild toxicity may result even after minimal exposures, but exact doses, especially in chronic exposures, are difficult to quantitate. The OSHA workplace permissible exposure limit for inorganic lead dust and fumes is 50 mcg/m(3) as an 8-hour time-weighted average. Concentrations of 100 mg/m(3) or more are considered immediately dangerous to life or health.
B) An adolescent developed only nausea and abdominal pain after ingesting 20 g of lead nitrate (12.6 g of lead). Her blood lead concentration was 20.4 mcmol/L (447 mg/dL) 90 minutes after ingestion. Following chelation therapy with calcium disodium EDTA for 5 days, she recovered completely
C) A preterm infant with severe congenital lead poisoning (cord blood lead 7.6 mcmol/L or 157.5 mcg/dL; BLL of 11.8 mcmol/L) recovered following chelation therapy.
D) A man with a history of schizophrenia developed severe lead poisoning (BLL 391 mcg/dL) after ingesting 206 22-caliber lead bullets. He recovered following aggressive GI decontamination and chelation therapy.
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