Acetyl Chloride

CAS RN: 75-36-5

Reactivities / Incompatibilities

Water reactive. Violent exothermic decomposition with water produces corrosive hydrochloric and acetic acids. Reacts violently with alcohols, alkalies, amines, and strong oxidizing materials.
Violent hydrolysis reaction with water or steam produces heat, acetic acid, hydrochloric acid (hcl), and other corrosive chlorides. Also incompatible with pcl3.
Decomposed violently by water or alcohol.
Use of a free flame instead of a heating bath to distill acetyl chloride produced from acetic acid and phosphorus trichloride caused the residual phosphonic (phosphorous) acid to decompose violently to give spontaneously flammable phosphine. Two later explosions in the same preparative system after reflux but before distillation from a water bath may have been due to ingress of air into the cooling flask and ignition of traces of phosphine.
Explosion hazard: by spontaneous chemical reaction, on contact with water, dimethyl sulfoxide or ethanol.
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