CAS RN: 94-59-7

Carcinogenicity Evidence

The Human Health Assessment Group in EPA's Office of Health and Environmental Assessment has evaluated safrole for carcinogenicity. According to their analysis, the weight-of-evidence for safrole is group B2, which is based on sufficient evidence in animals. No data are available in humans. As a group B2 chemical, safrole is considered probably carcinogenic to humans.
No data are available in humans. Sufficient evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 2B: The agent is possibly carcinogenic to humans.
Safrole: reasonably anticipated to be a human carcinogen.
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