Allyl Chloride

CAS RN: 107-05-1

Carcinogenicity Evidence

CLASSIFICATION: C; possible human carcinogen.
BASIS FOR CLASSIFICATION: Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens.
HUMAN CARCINOGENICITY DATA: None.
ANIMAL CARCINOGENICITY DATA: Limited.
Evaluation: There is inadequate evidence in humans for the carcinogenicity of allyl chloride. There is inadequate evidence in experimental animals for the carcinogenicity of allyl chloride. Overall evaluation: Allyl chloride is not classifiable as to its carcinogenicity to humans (Group 3).
A3; Confirmed animal carcinogen with unknown relevance to humans.
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