Paraquat

CAS RN: 4685-14-7

Laboratory

A) A full laboratory analysis, including liver function tests, basic metabolic panel, complete blood count, chest x-ray and urinalysis, should be performed on anyone ingesting paraquat. Arterial blood gas analysis should be performed on those with a late presentation or those with hypoxia. Those with chronic dermal exposures and systemic symptoms or those with hypoxia. Those with chronic dermal exposures and systemic symptoms should have the same testing as those acute ingestions. No testing is indicated in patients with acute dermal exposures without systemic symptoms.
B) Bedside testing can be performed using a 1% aqueous sodium dithionite in 0.1 normal sodium hydroxide to form a stable blue radical in the urine. If paraquat is present, the urine will appear blue compared with the control urine.
C) Serum paraquat concentrations (information available 24 hours a day 7 days a week through Zeneca Emergency Information Network, 1-800-327-8633, ctltestkitsupply@syngenta.com) can be useful for prognosis.
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